Mfsd8 | major facilitator superfamily domain containing 8
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Pigmentation Integument Vision/eye Behavior/neurological Cardiovascular system
13 No significant impact
5 Not tested
Data collections
Gene metrics:5Significant phenotypes
3Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues
| abnormal retina morphology | 1 supporting dataset | Mfsd8tm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.79x10-14 | ||
| abnormal retina vasculature morphology | 1 supporting dataset | Mfsd8tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.82x10-8 | ||
| increased circulating aspartate transaminase level | 1 supporting dataset | Mfsd8tm1b(EUCOMM)Hmgu | homozygote | Early adult | 9.61x10-7 | ||
| abnormal coat/hair pigmentation | 3 supporting datasets | Mfsd8tm1b(EUCOMM)Hmgu | homozygote | Early adult | 4.06x10-17 | ||
| impaired pupillary reflex | 1 supporting dataset | Mfsd8tm1b(EUCOMM)Hmgu | homozygote | Early adult | 7.83x10-16 |
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External links
No external links available for Mfsd8.
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| Mfsd8tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | es cell |
| Mfsd8tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Mfsd8tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Mfsd8tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |
| Mfsd8tm45701(L1L2_gt2) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |