Wdsub1 | WD repeat, SAM and U-box domain containing 1

GeneMGI:1919387Synonyms: 1700048E19Rik, 2610014F08Rik

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Limbs/digits/tail Vision/eye Behavior/neurological Skeleton Mortality/aging

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased startle reflex	1 supporting dataset	Wdsub1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	3.51x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Wdsub1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
long tibia	1 supporting dataset	Wdsub1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.14x10^-11
increased circulating creatinine level	1 supporting dataset	Wdsub1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.28x10^-5
decreased circulating serum albumin level	1 supporting dataset	Wdsub1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.28x10^-6
abnormal lens morphology	1 supporting dataset	Wdsub1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.16x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Wdsub1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Wdsub1.

IMPC related publications

Loading...

External links

No external links available for Wdsub1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Wdsub1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Wdsub1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

My Genes