Telo2 | telomere maintenance 2

GeneMGI:1918968Synonyms: 1200003M09Rik

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Adipose tissue Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetTelo2em1(IMPC)JhomozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetTelo2em1(IMPC)JhomozygoteE9.5N/A * 
increased total body fat amount1 supporting datasetTelo2em1(IMPC)JheterozygoteEarly adult5.44x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Telo2em1(IMPC)JExon Deletionmouse
Telo2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Telo2tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Telo2tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Telo2tm43325(L1L2_gt2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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