Prss54 | serine protease 54

GeneMGI:1918243Synonyms: 4931432M23Rik

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Immune system Endocrine/exocrine gland Integument Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged thymus	1 supporting dataset	Prss54^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Prss54^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Prss54^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
kyphosis	1 supporting dataset	Prss54^{em1(IMPC)Ccpcz}	homozygote	Early adult	9.72x10^-6
decreased memory-marker CD4-positive NK T cell number	1 supporting dataset	Prss54^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.45x10^-5
decreased NK T cell number	1 supporting dataset	Prss54^{em1(IMPC)Ccpcz}	homozygote	Early adult	7.64x10^-6
abnormal spine curvature	1 supporting dataset	Prss54^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.85x10^-5
decreased startle reflex	1 supporting dataset	Prss54^{em1(IMPC)Ccpcz}	homozygote	Early adult	8x10^-6
decreased CD4-positive NK T cell number	1 supporting dataset	Prss54^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.39x10^-5
abnormal heart morphology	1 supporting dataset	Prss54^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Prss54.

Associated images

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Histopathology

There is no histopathology data found for Prss54.

IMPC related publications

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External links

No external links available for Prss54.

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*Prss54^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Prss54^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Prss54^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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