Clic5 | chloride intracellular channel 5

GeneMGI:1917912Synonyms: nmf318, 5730531E12Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Nervous system Behavior/neurological Skeleton

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:50Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased bone mineral density	1 supporting dataset	Clic5^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.66x10^-5
decreased prepulse inhibition	4 supporting datasets	Clic5^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.39x10^-30
decreased startle reflex	1 supporting dataset	Clic5^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.21x10^-5
head bobbing	1 supporting dataset	Clic5^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.67x10^-10

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Clic5.

Associated images

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Histopathology

There is no histopathology data found for Clic5.

IMPC related publications

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External links

No external links available for Clic5.

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*Clic5^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Clic5^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Clic5^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Clic5^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Clic5^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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