Dcp2 | decapping mRNA 2

GeneMGI:1917890Synonyms: 2410015D23Rik, 5730537H01Rik

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Pigmentation Integument Growth/size/body region Mortality/aging Cardiovascular system

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal coat/hair pigmentation3 supporting datasetsDcp2tm1b(KOMP)WtsiheterozygoteEarly adult2.95x10-9 
increased heart weight1 supporting datasetDcp2tm1b(KOMP)WtsiheterozygoteEarly adult1.07x10-6 
preweaning lethality, complete penetrance1 supporting datasetDcp2tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dcp2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Dcp2tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Dcp2tm1e(KOMP)WtsiTargeted, non-conditional allelees cell

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