Mipep | mitochondrial intermediate peptidase

GeneMGI:1917728Synonyms: 5730405E07Rik

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Behavior/neurological Mortality/aging

17 No significant impact

3 Not tested

Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsMipepem1(IMPC)MbphomozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetMipepem1(IMPC)MbphomozygoteE9.5N/A * 
hydrometra1 supporting datasetMipepem1(IMPC)MbpheterozygoteEarly adultN/A * 
increased circulating serum albumin level1 supporting datasetMipepem1(IMPC)MbpheterozygoteEarly adult6.65x10-6 
increased startle reflex1 supporting datasetMipepem1(IMPC)MbpheterozygoteEarly adult1.43x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mipepem1(IMPC)MbpExon Deletionmouse
Mipeptm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Mipeptm1e(KOMP)MbpTargeted, non-conditional allelees cell
Mipeptm2a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Mipeptm2e(KOMP)MbpTargeted, non-conditional allelees cell

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