Tbce | tubulin-specific chaperone E

GeneMGI:1917680Synonyms: 2610206D02Rik, C530005D02Rik

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Mortality/aging

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
6Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

cataract1 supporting datasetTbcetm2b(EUCOMM)HmguheterozygoteEarly adult2.05x10-7 
preweaning lethality, complete penetrance1 supporting datasetTbcetm2b(EUCOMM)HmguhomozygoteEarly adultN/A * 
abnormal lens morphology1 supporting datasetTbcetm2b(EUCOMM)HmguheterozygoteEarly adult2x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tbcetm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Tbcetm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Tbcetm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Tbcetm2b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Tbcetm2e(EUCOMM)HmguTargeted, non-conditional allelees cell

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