Csnk1g3 | casein kinase 1, gamma 3

GeneMGI:1917675Synonyms: C330049O21Rik, 3300002K07Rik

Physiological systems

18 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Hearing/vestibular/ear Hematopoietic system Behavior/neurological Skeleton Craniofacial

11 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

absent pinna reflex1 supporting datasetCsnk1g3tm1a(EUCOMM)WtsihomozygoteEarly adult7.38x10-5 
decreased bone mineral content1 supporting datasetCsnk1g3tm1a(EUCOMM)WtsihomozygoteEarly adult1.08x10-6 
decreased circulating alkaline phosphatase level1 supporting datasetCsnk1g3tm1a(EUCOMM)WtsihomozygoteEarly adult1.71x10-6 
decreased hematocrit1 supporting datasetCsnk1g3tm1a(EUCOMM)WtsihomozygoteEarly adult7.34x10-5 
decreased erythrocyte cell number1 supporting datasetCsnk1g3tm1a(EUCOMM)WtsihomozygoteEarly adult2.44x10-5 
abnormal auditory brainstem response1 supporting datasetCsnk1g3tm1a(EUCOMM)WtsihomozygoteEarly adult2.94x10-7 
decreased circulating fructosamine level1 supporting datasetCsnk1g3tm1a(EUCOMM)WtsihomozygoteEarly adult2.86x10-5 
increased mean corpuscular hemoglobin1 supporting datasetCsnk1g3tm1a(EUCOMM)WtsihomozygoteEarly adult7.99x10-8 
abnormal cranium morphology1 supporting datasetCsnk1g3tm1a(EUCOMM)WtsihomozygoteEarly adult5.88x10-6 
increased circulating LDL cholesterol level1 supporting datasetCsnk1g3tm1a(EUCOMM)WtsihomozygoteEarly adult1.3x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Csnk1g3tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Csnk1g3tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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