Ubl7 | ubiquitin-like 7 (bone marrow stromal cell-derived)
Physiological systems
18 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system
10 No significant impact
6 Not tested
Data collections
Gene metrics:23Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased startle reflex | 1 supporting dataset | Ubl7em1(IMPC)Tcp | homozygote | Early adult | 9.6x10-6 | ||
| microphthalmia | 1 supporting dataset | Ubl7em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| increased hematocrit | 1 supporting dataset | Ubl7em1(IMPC)Tcp | homozygote | Early adult | 5.06x10-7 | ||
| narrow eye opening | 1 supporting dataset | Ubl7em1(IMPC)Tcp | homozygote | Early adult | 2x10-5 | ||
| increased mean corpuscular hemoglobin | 1 supporting dataset | Ubl7em1(IMPC)Tcp | homozygote | Early adult | 6.48x10-5 | ||
| prolonged RR interval | 1 supporting dataset | Ubl7em1(IMPC)Tcp | homozygote | Early adult | 2.9x10-6 | ||
| abnormal cornea morphology | 1 supporting dataset | Ubl7em1(IMPC)Tcp | homozygote | Early adult | 8.58x10-5 | ||
| increased mean corpuscular volume | 1 supporting dataset | Ubl7em1(IMPC)Tcp | homozygote | Early adult | 5.27x10-5 | ||
| increased hemoglobin content | 1 supporting dataset | Ubl7em1(IMPC)Tcp | homozygote | Early adult | 3.26x10-6 | ||
| increased blood urea nitrogen level | 1 supporting dataset | Ubl7em1(IMPC)Tcp | homozygote | Early adult | 2.59x10-8 |
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Human diseases caused by Ubl7 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Ubl7.
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| Ubl7em1(IMPC)Tcp | Exon Deletion | | mouse |
| Ubl7tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Ubl7tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |