Ubl7 | ubiquitin-like 7 (bone marrow stromal cell-derived)

GeneMGI:1916709Synonyms: 2300004C15Rik

Physiological systems

18 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

10 No significant impact

6 Not tested

Gene metrics:23Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased startle reflex1 supporting datasetUbl7em1(IMPC)TcphomozygoteEarly adult9.6x10-6 
microphthalmia1 supporting datasetUbl7em1(IMPC)TcphomozygoteEarly adultN/A * 
increased hematocrit1 supporting datasetUbl7em1(IMPC)TcphomozygoteEarly adult5.06x10-7 
narrow eye opening1 supporting datasetUbl7em1(IMPC)TcphomozygoteEarly adult2x10-5 
increased mean corpuscular hemoglobin1 supporting datasetUbl7em1(IMPC)TcphomozygoteEarly adult6.48x10-5 
prolonged RR interval1 supporting datasetUbl7em1(IMPC)TcphomozygoteEarly adult2.9x10-6 
abnormal cornea morphology1 supporting datasetUbl7em1(IMPC)TcphomozygoteEarly adult8.58x10-5 
increased mean corpuscular volume1 supporting datasetUbl7em1(IMPC)TcphomozygoteEarly adult5.27x10-5 
increased hemoglobin content1 supporting datasetUbl7em1(IMPC)TcphomozygoteEarly adult3.26x10-6 
increased blood urea nitrogen level1 supporting datasetUbl7em1(IMPC)TcphomozygoteEarly adult2.59x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ubl7em1(IMPC)TcpExon Deletionmouse
Ubl7tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ubl7tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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