Ptms | parathymosin

GeneMGI:1916452Synonyms: 2610009E16Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Mortality/aging Renal/urinary system

14 No significant impact

6 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:50Adult tissues
25Embryo tissues

Phenotypes

abnormal behavior1 supporting datasetPtmstm1.1(KOMP)WtsiheterozygoteEarly adult2.58x10-6 
decreased thigmotaxis2 supporting datasetsPtmstm1.1(KOMP)WtsiheterozygoteEarly adult2.57x10-6 
hyperactivity8 supporting datasetsPtmstm1.1(KOMP)WtsiheterozygoteEarly adult1.96x10-21 
decreased exploration in new environment1 supporting datasetPtmstm1.1(KOMP)WtsiheterozygoteEarly adult3.54x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetPtmstm1.1(KOMP)WtsihomozygoteEarly adultN/A * 
increased circulating phosphate level1 supporting datasetPtmstm1.1(KOMP)WtsiheterozygoteEarly adult1.07x10-6 
decreased urine magnesium level1 supporting datasetPtmstm1.1(KOMP)WtsiheterozygoteEarly adult4.86x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ptmstm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
mouse
Ptmstm1.1(KOMP)WtsiReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Ptmstm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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