Arv1 | ARV1 homolog, fatty acid homeostasis modulator

GeneMGI:1916115Synonyms: 1110067L22Rik

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Hearing/vestibular/ear Vision/eye Behavior/neurological Skeleton Cardiovascular system

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased bone mineral density1 supporting datasetArv1em1(IMPC)JhomozygoteEarly adult6.82x10-6 
abnormal auditory brainstem response4 supporting datasetsArv1em1(IMPC)JhomozygoteEarly adult4.3x10-9 
increased grip strength1 supporting datasetArv1em1(IMPC)JhomozygoteEarly adult9.53x10-6 
hyperactivity7 supporting datasetsArv1em1(IMPC)JhomozygoteEarly adult1.04x10-27 
decreased heart rate1 supporting datasetArv1em1(IMPC)JhomozygoteEarly adult2.85x10-5 
prolonged RR interval1 supporting datasetArv1em1(IMPC)JhomozygoteEarly adult2.8x10-5 
increased thigmotaxis2 supporting datasetsArv1em1(IMPC)JhomozygoteEarly adult8.38x10-5 
cataract1 supporting datasetArv1em1(IMPC)JhomozygoteEarly adult7.17x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Arv1em1(IMPC)JExon Deletionmouse
Arv1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Arv1tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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