Tppp3 | tubulin polymerization-promoting protein family member 3

GeneMGI:1915221Synonyms: 2700055K07Rik

Physiological systems

22 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Immune system Endocrine/exocrine gland Growth/size/body region Limbs/digits/tail Hematopoietic system Skeleton Craniofacial Mortality/aging

14 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased CD4-positive NK T cell number	1 supporting dataset	Tppp3^{em1(IMPC)Ccpcz}	heterozygote	Early adult	1.99x10^-5
enlarged spleen	1 supporting dataset	Tppp3^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
increased memory-marker CD4-positive NK T cell number	1 supporting dataset	Tppp3^{em1(IMPC)Ccpcz}	heterozygote	Early adult	1.37x10^-5
abnormal digit morphology	1 supporting dataset	Tppp3^{em1(IMPC)Ccpcz}	heterozygote	Early adult	4.33x10^-5
abnormal lymph node morphology	1 supporting dataset	Tppp3^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal thymus morphology	2 supporting datasets	Tppp3^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Tppp3^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
enlarged thymus	2 supporting datasets	Tppp3^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal tooth morphology	1 supporting dataset	Tppp3^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Tppp3^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tppp3.

Associated images

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Histopathology

There is no histopathology data found for Tppp3.

IMPC related publications

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External links

No external links available for Tppp3.

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*Tppp3^{em1(IMPC)Ccpcz}*	Intra-exon deletion	‌	mouse
*Tppp3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Tppp3^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell

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