Tmem70 | transmembrane protein 70

GeneMGI:1915068Synonyms: 1110020A09Rik, 2210416J16Rik

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Embryo Growth/size/body region Nervous system Mortality/aging Craniofacial

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal embryo turning	1 supporting dataset	Tmem70^em2(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal neural tube morphology	1 supporting dataset	Tmem70^em2(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal somite shape	1 supporting dataset	Tmem70^em2(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal embryo turning	1 supporting dataset	Tmem70^em2(IMPC)Bay	heterozygote	E9.5	N/A ^*
abnormal embryo size	1 supporting dataset	Tmem70^em2(IMPC)Bay	homozygote	E9.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Tmem70^em2(IMPC)Bay	heterozygote	E9.5	N/A ^*
abnormal embryo size	1 supporting dataset	Tmem70^em2(IMPC)Bay	heterozygote	E9.5	N/A ^*
abnormal embryo development	1 supporting dataset	Tmem70^em2(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal pharyngeal arch morphology	1 supporting dataset	Tmem70^em2(IMPC)Bay	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Tmem70^em2(IMPC)Bay	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmem70.

Associated images

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Histopathology

There is no histopathology data found for Tmem70.

IMPC related publications

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External links

No external links available for Tmem70.

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*Tmem70^em1(IMPC)Bay*		‌	mouse
*Tmem70^em2(IMPC)Bay*	Exon Deletion	‌	mouse
*Tmem70^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Tmem70^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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