Tctn3 | tectonic family member 3
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Limbs/digits/tail Vision/eye Mortality/aging
13 No significant impact
5 Not tested
Data collections
Gene metrics:9Significant phenotypes
6Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal embryo size | 1 supporting dataset | Tctn3em1(IMPC)J | homozygote | E18.5 | N/A * | ||
| abnormal cholesterol homeostasis | 1 supporting dataset | Tctn3em1(IMPC)J | heterozygote | Early adult | 1.12x10-5 | ||
| polydactyly | 1 supporting dataset | Tctn3em1(IMPC)J | homozygote | E18.5 | N/A * | ||
| anophthalmia | 1 supporting dataset | Tctn3em1(IMPC)J | homozygote | E18.5 | N/A * | ||
| abnormal lens morphology | 1 supporting dataset | Tctn3em1(IMPC)J | heterozygote | Late adult | 2.08x10-6 | ||
| decreased circulating calcium level | 1 supporting dataset | Tctn3em1(IMPC)J | heterozygote | Early adult | 3.42x10-12 | ||
| decreased circulating total protein level | 1 supporting dataset | Tctn3em1(IMPC)J | heterozygote | Early adult | 1.7x10-11 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Tctn3em1(IMPC)J | homozygote | Early adult | N/A * | ||
| abnormal body wall morphology | 1 supporting dataset | Tctn3em1(IMPC)J | homozygote | E18.5 | N/A * |
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External links
No external links available for Tctn3.
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| Tctn3em1(IMPC)J | Exon Deletion | | mouse |
| Tctn3tm47188(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |