Zc3h13 | zinc finger CCCH type containing 13

GeneMGI:1914552Synonyms: C87618, 3110050K21Rik, +2 more

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Embryo Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Mortality/aging

11 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal coat/ hair morphology	1 supporting dataset	Zc3h13^em1(IMPC)J	heterozygote	Early adult	5.61x10^-6
abnormal vocalization	1 supporting dataset	Zc3h13^em1(IMPC)J	heterozygote	Early adult	9.21x10^-7
decreased hemoglobin content	1 supporting dataset	Zc3h13^em1(IMPC)J	heterozygote	Early adult	5.93x10^-7
abnormal embryo size	1 supporting dataset	Zc3h13^em1(IMPC)J	homozygote	E9.5	N/A ^*
prenatal lethality prior to heart atrial septation	1 supporting dataset	Zc3h13^em1(IMPC)J	homozygote	E15.5	N/A ^*
abnormal coat/hair pigmentation	1 supporting dataset	Zc3h13^em1(IMPC)J	heterozygote	Early adult	9.27x10^-8
increased circulating cholesterol level	1 supporting dataset	Zc3h13^em1(IMPC)J	heterozygote	Early adult	1.65x10^-7
increased circulating HDL cholesterol level	1 supporting dataset	Zc3h13^em1(IMPC)J	heterozygote	Early adult	1.22x10^-8
preweaning lethality, complete penetrance	1 supporting dataset	Zc3h13^em1(IMPC)J	homozygote	Early adult	N/A ^*
embryonic growth retardation	1 supporting dataset	Zc3h13^em1(IMPC)J	homozygote	E12.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Zc3h13.

Associated images

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Histopathology

There is no histopathology data found for Zc3h13.

IMPC related publications

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External links

No external links available for Zc3h13.

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*Zc3h13^em1(IMPC)J*	Exon Deletion	‌	mouse
*Zc3h13^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Zc3h13^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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