Bmerb1 | bMERB domain containing 1
Physiological systems
22 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Endocrine/exocrine gland Digestive/alimentary Hearing/vestibular/ear Renal/urinary system
18 No significant impact
2 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal auditory brainstem response | 1 supporting dataset | Bmerb1em1(IMPC)Ccpcz | homozygote | Early adult | 2.26x10-8 | ||
| abnormal urinary bladder morphology | 1 supporting dataset | Bmerb1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| abnormal adrenal gland morphology | 1 supporting dataset | Bmerb1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| enlarged adrenal glands | 1 supporting dataset | Bmerb1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| abnormal salivary gland morphology | 1 supporting dataset | Bmerb1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * |
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Human diseases caused by Bmerb1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Bmerb1.
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| Bmerb1em1(IMPC)Ccpcz | Indel | | mouse |
| Bmerb1tm378600(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |