Yipf5 | Yip1 domain family, member 5

GeneMGI:1914430Synonyms: 2610311I19Rik, Yip1a

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Nervous system Vision/eye Hematopoietic system Mortality/aging Cardiovascular system

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

22Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased erythrocyte cell number	1 supporting dataset	Yipf5^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	8.56x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Yipf5^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Yipf5^{tm1b(EUCOMM)Hmgu}	homozygote	E12.5	N/A ^*
decreased total retina thickness	2 supporting datasets	Yipf5^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.83x10^-5
abnormal retina outer nuclear layer morphology	1 supporting dataset	Yipf5^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	6.73x10^-8
increased prepulse inhibition	1 supporting dataset	Yipf5^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	6.52x10^-6
embryonic lethality prior to organogenesis	1 supporting dataset	Yipf5^{tm1b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*
thick ventricular wall	1 supporting dataset	Yipf5^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.9x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Yipf5.

Associated images

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Histopathology

There is no histopathology data found for Yipf5.

IMPC related publications

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External links

No external links available for Yipf5.

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*Yipf5^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Yipf5^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Yipf5^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Yipf5^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Yipf5^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Yipf5^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Yipf5^{tm3a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Yipf5^{tm3e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

My Genes