Arl8b | ADP-ribosylation factor-like 8B

GeneMGI:1914416Synonyms: 3100002J04Rik, Arl10c, +1 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Nervous system Skeleton Mortality/aging

13 No significant impact

7 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased prepulse inhibition2 supporting datasetsArl8btm1.1(NCOM)MfgcheterozygoteEarly adult2.4x10-5 
abnormal pelvic girdle bone morphology1 supporting datasetArl8btm1.1(NCOM)MfgchomozygoteEarly adult3.29x10-5 
increased fasting circulating glucose level1 supporting datasetArl8btm1.1(NCOM)MfgcheterozygoteEarly adult6.71x10-5 
preweaning lethality, incomplete penetrance2 supporting datasetsArl8btm1.1(NCOM)MfgchomozygoteEarly adultN/A * 
increased blood urea nitrogen level1 supporting datasetArl8btm1.1(NCOM)MfgcheterozygoteEarly adult2.01x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Arl8btm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
mouse
Arl8btm1.1(NCOM)MfgcReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Arl8btm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Arl8btm367356(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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