Ankrd12 | ankyrin repeat domain 12

GeneMGI:1914357Synonyms: 2900001A12Rik, ANCO-2, +1 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Hematopoietic system Cardiovascular system

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

thrombocytosis1 supporting datasetAnkrd12tm1a(EUCOMM)WtsiheterozygoteEarly adult9.87x10-5 
increased heart weight1 supporting datasetAnkrd12tm1a(EUCOMM)WtsiheterozygoteEarly adult8.32x10-5 
decreased circulating cholesterol level1 supporting datasetAnkrd12tm1a(EUCOMM)WtsiheterozygoteEarly adult1.53x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ankrd12tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse

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