Romo1 | reactive oxygen species modulator 1

GeneMGI:1914317Synonyms: 2010100O12Rik

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Embryo Growth/size/body region Behavior/neurological Mortality/aging Cardiovascular system

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

pale yolk sac1 supporting datasetRomo1em1(IMPC)KmpchomozygoteE9.5N/A * 
abnormal vitelline vasculature morphology1 supporting datasetRomo1em1(IMPC)KmpchomozygoteE9.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetRomo1em1(IMPC)KmpchomozygoteEarly adultN/A * 
increased circulating creatine kinase level1 supporting datasetRomo1em1(IMPC)KmpcheterozygoteEarly adult5.2x10-6 
hyperactivity2 supporting datasetsRomo1em1(IMPC)KmpcheterozygoteEarly adult2.46x10-5 
embryonic growth retardation1 supporting datasetRomo1em1(IMPC)KmpchomozygoteE9.5N/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetRomo1em1(IMPC)KmpchomozygoteE12.5N/A * 
abnormal embryo size1 supporting datasetRomo1em1(IMPC)KmpchomozygoteE9.5N/A * 
embryonic lethality prior to organogenesis1 supporting datasetRomo1em1(IMPC)KmpchomozygoteE9.5N/A * 
increased circulating total protein level1 supporting datasetRomo1em1(IMPC)KmpcheterozygoteEarly adult2.21x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Romo1em1(IMPC)KmpcDeletionmouse
Romo1tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
es cell

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