Romo1 | reactive oxygen species modulator 1

GeneMGI:1914317Synonyms: 2010100O12Rik

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Embryo Growth/size/body region Behavior/neurological Mortality/aging Cardiovascular system

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



pale yolk sac	1 supporting dataset	Romo1^{em1(IMPC)Kmpc}	homozygote	E9.5	N/A ^*
abnormal vitelline vasculature morphology	1 supporting dataset	Romo1^{em1(IMPC)Kmpc}	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Romo1^{em1(IMPC)Kmpc}	homozygote	Early adult	N/A ^*
increased circulating creatine kinase level	1 supporting dataset	Romo1^{em1(IMPC)Kmpc}	heterozygote	Early adult	5.2x10^-6
hyperactivity	2 supporting datasets	Romo1^{em1(IMPC)Kmpc}	heterozygote	Early adult	2.46x10^-5
embryonic growth retardation	1 supporting dataset	Romo1^{em1(IMPC)Kmpc}	homozygote	E9.5	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Romo1^{em1(IMPC)Kmpc}	homozygote	E12.5	N/A ^*
abnormal embryo size	1 supporting dataset	Romo1^{em1(IMPC)Kmpc}	homozygote	E9.5	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Romo1^{em1(IMPC)Kmpc}	homozygote	E9.5	N/A ^*
increased circulating total protein level	1 supporting dataset	Romo1^{em1(IMPC)Kmpc}	heterozygote	Early adult	2.21x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Romo1.

Associated images

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Histopathology

There is no histopathology data found for Romo1.

IMPC related publications

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External links

No external links available for Romo1.

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*Romo1^{em1(IMPC)Kmpc}*	Deletion	‌	mouse
*Romo1^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell

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