Nek7 | NIMA (never in mitosis gene a)-related expressed kinase 7

GeneMGI:1890645Synonyms: 2810460C19Rik

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging Renal/urinary system

18 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased urine microalbumin level	1 supporting dataset	Nek7^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	8.33x10^-9
preweaning lethality, complete penetrance	1 supporting dataset	Nek7^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nek7.

Associated images

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Histopathology

There is no histopathology data found for Nek7.

IMPC related publications

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External links

No external links available for Nek7.

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*Nek7^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Nek7^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Nek7^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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