Extl3 | exostosin-like glycosyltransferase 3
Physiological systems
21 / 24 physiological systems tested
10 Significantly impacted by the knock-out
Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Mortality/aging Renal/urinary system
11 No significant impact
3 Not tested
Data collections
Gene metrics:14Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
small testis | 1 supporting dataset | Extl3em1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
abnormal skin morphology | 1 supporting dataset | Extl3em1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
abnormal liver morphology | 1 supporting dataset | Extl3em1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
abnormal kidney morphology | 2 supporting datasets | Extl3em1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Extl3em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
small kidney | 1 supporting dataset | Extl3em1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
enlarged spleen | 1 supporting dataset | Extl3em1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
abnormal eye morphology | 1 supporting dataset | Extl3em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
enlarged liver | 1 supporting dataset | Extl3em1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
embryonic lethality prior to organogenesis | 1 supporting dataset | Extl3em1(IMPC)Mbp | homozygote | E9.5 | N/A * |
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External links
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Extl3em1(IMPC)Mbp | Intra-exon deletion | | mouse |