Extl3 | exostosin-like glycosyltransferase 3

GeneMGI:1860765Synonyms: 2900009G18Rik

Physiological systems

21 / 24 physiological systems tested

10 Significantly impacted by the knock-out

 Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Mortality/aging Renal/urinary system

11 No significant impact

3 Not tested

Gene metrics:14Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

small testis1 supporting datasetExtl3em1(IMPC)MbpheterozygoteLate adultN/A * 
abnormal skin morphology1 supporting datasetExtl3em1(IMPC)MbpheterozygoteLate adultN/A * 
abnormal liver morphology1 supporting datasetExtl3em1(IMPC)MbpheterozygoteLate adultN/A * 
abnormal kidney morphology2 supporting datasetsExtl3em1(IMPC)MbpheterozygoteLate adultN/A * 
preweaning lethality, complete penetrance3 supporting datasetsExtl3em1(IMPC)MbphomozygoteEarly adultN/A * 
small kidney1 supporting datasetExtl3em1(IMPC)MbpheterozygoteLate adultN/A * 
enlarged spleen1 supporting datasetExtl3em1(IMPC)MbpheterozygoteLate adultN/A * 
abnormal eye morphology1 supporting datasetExtl3em1(IMPC)MbpheterozygoteEarly adultN/A * 
enlarged liver1 supporting datasetExtl3em1(IMPC)MbpheterozygoteLate adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetExtl3em1(IMPC)MbphomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Extl3em1(IMPC)MbpIntra-exon deletionmouse

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