Nfat5 | nuclear factor of activated T cells 5
Physiological systems
18 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Mortality/aging
15 No significant impact
6 Not tested
Data collections
Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:48Adult tissues
51Embryo tissues
| increased circulating chloride level | 1 supporting dataset | Nfat5tm1b(KOMP)Wtsi | heterozygote | Early adult | 6.83x10-8 | ||
| increased circulating bilirubin level | 1 supporting dataset | Nfat5tm1b(KOMP)Wtsi | heterozygote | Early adult | 6.39x10-5 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Nfat5tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| increased circulating sodium level | 1 supporting dataset | Nfat5tm1b(KOMP)Wtsi | heterozygote | Early adult | 8.57x10-10 | ||
| improved glucose tolerance | 1 supporting dataset | Nfat5tm1b(KOMP)Wtsi | heterozygote | Early adult | 1.17x10-6 | ||
| decreased hematocrit | 1 supporting dataset | Nfat5tm1b(KOMP)Wtsi | heterozygote | Early adult | 1.22x10-5 |
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External links
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| Nfat5tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Nfat5tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Nfat5tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |