Acsl4 | acyl-CoA synthetase long-chain family member 4

GeneMGI:1354713Synonyms: Facl4, 9430020A05Rik, +2 more

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Limbs/digits/tail Hematopoietic system Skeleton Mortality/aging

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal tibia morphology	1 supporting dataset	Acsl4^{tm1a(EUCOMM)Wtsi}	hemizygote	Early adult	8.36x10^-5
decreased circulating chloride level	1 supporting dataset	Acsl4^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	7.07x10^-5
increased total body fat amount	1 supporting dataset	Acsl4^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.29x10^-5
decreased body weight	3 supporting datasets	Acsl4^{tm1a(EUCOMM)Wtsi}	hemizygote	Early adult	7.44x10^-6
thrombocytopenia	1 supporting dataset	Acsl4^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	9.29x10^-5
decreased body length	1 supporting dataset	Acsl4^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.1x10^-11
preweaning lethality, incomplete penetrance	1 supporting dataset	Acsl4^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Acsl4.

Associated images

Loading...

Histopathology

There is no histopathology data found for Acsl4.

IMPC related publications

Loading...

External links

No external links available for Acsl4.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Acsl4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse

My Genes