Pik3cg | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma

GeneMGI:1353576Synonyms: PI3Kgamma, PI(3)Kgamma, +3 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Skeleton

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

1Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased bone mineral density	1 supporting dataset	Pik3cg^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.17x10^-5
decreased circulating potassium level	1 supporting dataset	Pik3cg^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	9.53x10^-5
increased body length	1 supporting dataset	Pik3cg^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.14x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pik3cg.

Associated images

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Histopathology

There is no histopathology data found for Pik3cg.

IMPC related publications

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External links

No external links available for Pik3cg.

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*Pik3cg^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Pik3cg^{tm1c(EUCOMM)Wtsi}*	Wild type floxed exon (post-Flp)	‌	mouse
*Pik3cg^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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