Abcc8 | ATP-binding cassette, sub-family C member 8

GeneMGI:1352629Synonyms: Sur, D930031B21Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

12Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



impaired glucose tolerance	2 supporting datasets	Abcc8^em1(IMPC)J	homozygote	Early adult	1.93x10^-21
increased lean body mass	1 supporting dataset	Abcc8^em1(IMPC)J	homozygote	Early adult	7.48x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Abcc8.

Associated images

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Histopathology

There is no histopathology data found for Abcc8.

IMPC related publications

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External links

No external links available for Abcc8.

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*Abcc8^em1(IMPC)J*	Exon Deletion	‌	mouse
*Abcc8^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Abcc8^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell
*Abcc8^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Abcc8^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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