Atp5mg | ATP synthase membrane subunit g

GeneMGI:1351597Synonyms: F1F0-ATP synthase g subunit, 4933437C06Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Behavior/neurological Mortality/aging Cardiovascular system

12 No significant impact

5 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
21Embryo tissues

Phenotypes

decreased eosinophil cell number1 supporting datasetAtp5mgtm1b(EUCOMM)HmguheterozygoteEarly adult8.22x10-9 
preweaning lethality, complete penetrance1 supporting datasetAtp5mgtm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
increased blood urea nitrogen level1 supporting datasetAtp5mgtm1b(EUCOMM)HmguheterozygoteEarly adult2.6x10-6 
increased mean corpuscular hemoglobin1 supporting datasetAtp5mgtm1b(EUCOMM)HmguheterozygoteEarly adult1.81x10-5 
enlarged heart1 supporting datasetAtp5mgtm1b(EUCOMM)HmguheterozygoteEarly adultN/A * 
abnormal gait1 supporting datasetAtp5mgtm1b(EUCOMM)HmguheterozygoteEarly adult4.79x10-6 
increased circulating serum albumin level1 supporting datasetAtp5mgtm1b(EUCOMM)HmguheterozygoteEarly adult4.17x10-5 
enlarged spleen1 supporting datasetAtp5mgtm1b(EUCOMM)HmguheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Atp5mgtm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Atp5mgtm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Atp5mgtm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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