Srp9 | signal recognition particle 9

GeneMGI:1350930Synonyms: 9kDa

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

17 No significant impact

5 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

decreased fasting circulating glucose level1 supporting datasetSrp9tm1.1(KOMP)VlcgheterozygoteEarly adult1.09x10-5 
increased circulating chloride level1 supporting datasetSrp9tm1.1(KOMP)VlcgheterozygoteEarly adult7.94x10-5 
preweaning lethality, complete penetrance1 supporting datasetSrp9tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetSrp9tm1.1(KOMP)VlcghomozygoteE9.5N/A * 
increased circulating aspartate transaminase level1 supporting datasetSrp9tm1.1(KOMP)VlcgheterozygoteEarly adult8.78x10-6 
embryonic lethality prior to tooth bud stage1 supporting datasetSrp9tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Srp9tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Srp9tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Srp9tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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