Spo11 | SPO11 initiator of meiotic double stranded breaks
Physiological systems
8 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Immune system Growth/size/body region Hematopoietic system
5 No significant impact
16 Not tested
Data collections
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues
| increased spleen weight | 1 supporting dataset | Spo11tm2b(KOMP)Wtsi | homozygote | Early adult | 5.09x10-5 | ||
| abnormal spleen morphology | 2 supporting datasets | Spo11tm2b(KOMP)Wtsi | homozygote | Early adult | N/A * |
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External links
No external links available for Spo11.
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| Spo11tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Spo11tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Spo11tm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Spo11tm2b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Spo11tm2e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Spo11tm94179(L1L2_Pgk_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |