Mecr | mitochondrial trans-2-enoyl-CoA reductase

GeneMGI:1349441Synonyms: Nrbf1

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Behavior/neurological Mortality/aging

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

3Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal response to tactile stimuli	1 supporting dataset	Mecr^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	6.64x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Mecr^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal gait	1 supporting dataset	Mecr^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.48x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* Does not have a P-value assigned because it was manually marked as significant.

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lacZ Expression

No adult expression data available for Mecr.

Associated images

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Histopathology

There is no histopathology data found for Mecr.

IMPC related publications

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External links

No external links available for Mecr.

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*Mecr^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Mecr^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Mecr^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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