Cops4 | COP9 signalosome subunit 4
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Hematopoietic system Behavior/neurological Mortality/aging
17 No significant impact
4 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal behavior | 2 supporting datasets | Cops4tm1a(EUCOMM)Hmgu | heterozygote | Early adult | 2.82x10-6 | ||
| decreased locomotor activity | 2 supporting datasets | Cops4tm1a(EUCOMM)Hmgu | heterozygote | Early adult | 4.48x10-7 | ||
| increased startle reflex | 5 supporting datasets | Cops4tm1a(EUCOMM)Hmgu | heterozygote | Early adult | 5.83x10-13 | ||
| increased hemoglobin content | 1 supporting dataset | Cops4tm1a(EUCOMM)Hmgu | heterozygote | Early adult | 6.28x10-7 | ||
| increased mean corpuscular hemoglobin concentration | 1 supporting dataset | Cops4tm1a(EUCOMM)Hmgu | heterozygote | Early adult | 1.86x10-7 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Cops4tm1a(EUCOMM)Hmgu | homozygote | Early adult | N/A * |
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External links
No external links available for Cops4.
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| Cops4tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Cops4tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |
| Cops4tm44610(L1L2_gt2) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |