Hsf4 | heat shock transcription factor 4
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Pigmentation Growth/size/body region Vision/eye Cardiovascular system
12 No significant impact
7 Not tested
Data collections
Gene metrics:7Significant phenotypes
3Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues
| increased heart weight | 1 supporting dataset | Hsf4tm1b(KOMP)Wtsi | homozygote | Early adult | 6.5x10-5 | ||
| abnormal lens morphology | 1 supporting dataset | Hsf4tm1b(KOMP)Wtsi | homozygote | Early adult | 2.14x10-16 | ||
| irregularly shaped pupil | 1 supporting dataset | Hsf4tm1b(KOMP)Wtsi | homozygote | Early adult | 1.55x10-5 | ||
| increased circulating alanine transaminase level | 1 supporting dataset | Hsf4tm1b(KOMP)Wtsi | homozygote | Early adult | 1.23x10-5 | ||
| abnormal iris pigmentation | 1 supporting dataset | Hsf4tm1b(KOMP)Wtsi | homozygote | Early adult | 1x10-20 | ||
| cataract | 1 supporting dataset | Hsf4tm1b(KOMP)Wtsi | homozygote | Early adult | 1.31x10-18 | ||
| abnormal cornea morphology | 1 supporting dataset | Hsf4tm1b(KOMP)Wtsi | homozygote | Early adult | 9.48x10-6 |
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External links
No external links available for Hsf4.
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| Hsf4tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Hsf4tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Hsf4tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |