Slc30a4 | solute carrier family 30 (zinc transporter), member 4

GeneMGI:1345282Synonyms: Znt4

Physiological systems

19 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Limbs/digits/tail Hematopoietic system Behavior/neurological Skeleton Renal/urinary system

9 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



decreased grip strength	1 supporting dataset	Slc30a4^em1(IMPC)Tcp	homozygote	Early adult	6.24x10^-6
short tibia	1 supporting dataset	Slc30a4^em1(IMPC)Tcp	homozygote	Early adult	1.22x10^-12
increased grip strength	1 supporting dataset	Slc30a4^em1(IMPC)Tcp	homozygote	Late adult	6.09x10^-6
tremors	1 supporting dataset	Slc30a4^em1(IMPC)Tcp	homozygote	Late adult	7.59x10^-6
small thymus	1 supporting dataset	Slc30a4^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Slc30a4^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal ovary morphology	1 supporting dataset	Slc30a4^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
short tibia	1 supporting dataset	Slc30a4^em1(IMPC)Tcp	homozygote	Late adult	6.21x10^-7
small adrenal glands	1 supporting dataset	Slc30a4^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
enlarged kidney	1 supporting dataset	Slc30a4^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Slc30a4.

Associated images

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Histopathology

There is no histopathology data found for Slc30a4.

IMPC related publications

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External links

No external links available for Slc30a4.

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*Slc30a4^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Slc30a4^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Slc30a4^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Slc30a4^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Slc30a4^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Slc30a4^{tm43906(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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