Lamc3 | laminin gamma 3

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Hematopoietic system Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased grip strength1 supporting datasetLamc3tm1a(KOMP)WtsihomozygoteEarly adult9.71x10-5 
thrombocytopenia1 supporting datasetLamc3tm1a(KOMP)WtsihomozygoteEarly adult3.29x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lamc3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Lamc3tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Lamc3tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Lamc3tm295536(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Lamc3tm33982(L1L2_st1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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