Padi3 | peptidyl arginine deiminase, type III

GeneMGI:1338891Synonyms: Pdi3, PAD type III, +1 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Growth/size/body region Hearing/vestibular/ear

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal auditory brainstem response1 supporting datasetPadi3tm1b(KOMP)WtsihomozygoteEarly adult6.33x10-5 
decreased lean body mass2 supporting datasetsPadi3tm1b(KOMP)WtsihomozygoteEarly adult3.21x10-5 
increased circulating HDL cholesterol level1 supporting datasetPadi3tm1b(KOMP)WtsihomozygoteEarly adult9.98x10-5 
increased total body fat amount2 supporting datasetsPadi3tm1b(KOMP)WtsihomozygoteEarly adult1.71x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Padi3tm119234(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Padi3tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Padi3tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Padi3tm2e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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