Gnb1l | guanine nucleotide binding protein (G protein), beta polypeptide 1-like

GeneMGI:1338057Synonyms: ESTM55, Wdr14, +2 more

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Embryo Growth/size/body region Nervous system Vision/eye Mortality/aging Cardiovascular system

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal neural tube morphology	1 supporting dataset	Gnb1l^em1(IMPC)Tcp	heterozygote	E9.5	N/A ^*
abnormal embryo size	1 supporting dataset	Gnb1l^em1(IMPC)Tcp	heterozygote	E9.5	N/A ^*
abnormal retina blood vessel morphology	2 supporting datasets	Gnb1l^em1(IMPC)Tcp	heterozygote	Early adult	1.52x10^-6
abnormal midbrain development	1 supporting dataset	Gnb1l^em1(IMPC)Tcp	heterozygote	E9.5	N/A ^*
abnormal forebrain development	1 supporting dataset	Gnb1l^em1(IMPC)Tcp	heterozygote	E9.5	N/A ^*
abnormal hindbrain development	1 supporting dataset	Gnb1l^em1(IMPC)Tcp	heterozygote	E9.5	N/A ^*
abnormal retina vasculature morphology	1 supporting dataset	Gnb1l^em1(IMPC)Tcp	heterozygote	Early adult	2.42x10^-5
preweaning lethality, complete penetrance	3 supporting datasets	Gnb1l^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Gnb1l.

Associated images

Loading...

Histopathology

There is no histopathology data found for Gnb1l.

IMPC related publications

Loading...

External links

No external links available for Gnb1l.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Gnb1l^em1(IMPC)Tcp*	Insertion, Intragenic deletion	‌	mouse
*Gnb1l^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Gnb1l^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Gnb1l^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell

My Genes