Bex3 | brain expressed X-linked 3

GeneMGI:1338016Synonyms: p75NTR-associated Cell Death Executor, Ngfrap1, +3 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Integument Growth/size/body region Vision/eye Renal/urinary system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



small kidney	1 supporting dataset	Bex3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
cataract	1 supporting dataset	Bex3^em1(IMPC)Mbp	homozygote	Early adult	1.36x10^-5
abnormal kidney morphology	1 supporting dataset	Bex3^em1(IMPC)Mbp	hemizygote	Early adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Bex3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	Bex3^em1(IMPC)Mbp	homozygote	Early adult	1.63x10^-5
microphthalmia	1 supporting dataset	Bex3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	Bex3^em1(IMPC)Mbp	hemizygote	Early adult	5.99x10^-5
enlarged kidney	1 supporting dataset	Bex3^em1(IMPC)Mbp	hemizygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Bex3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
cataract	1 supporting dataset	Bex3^em1(IMPC)Mbp	hemizygote	Early adult	6.35x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Bex3.

Associated images

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Histopathology

There is no histopathology data found for Bex3.

IMPC related publications

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External links

No external links available for Bex3.

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*Bex3^em1(IMPC)Mbp*	Whole-gene deletion	‌	mouse
*Bex3^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell
*Bex3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell

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