Serf1 | small EDRK-rich factor 1
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Skeleton Cardiovascular system
13 No significant impact
5 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased circulating cholesterol level | 1 supporting dataset | Serf1tm1a(EUCOMM)Hmgu | homozygote | Early adult | 5.6x10-12 | ||
| decreased bone mineral density | 1 supporting dataset | Serf1tm1a(EUCOMM)Hmgu | homozygote | Early adult | 2.2x10-5 | ||
| increased circulating HDL cholesterol level | 1 supporting dataset | Serf1tm1a(EUCOMM)Hmgu | homozygote | Early adult | 1.67x10-11 | ||
| increased heart weight | 1 supporting dataset | Serf1tm1a(EUCOMM)Hmgu | homozygote | Early adult | 4.88x10-5 | ||
| decreased CD8-positive, alpha-beta T cell number | 1 supporting dataset | Serf1tm1a(EUCOMM)Hmgu | homozygote | Early adult | 2.3x10-5 |
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External links
No external links available for Serf1.
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| Serf1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | es cell |
| Serf1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Serf1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |