Ncor2 | nuclear receptor co-repressor 2
Physiological systems
22 / 24 physiological systems tested
11 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Behavior/neurological Skeleton Cardiovascular system Craniofacial Mortality/aging
11 No significant impact
2 Not tested
Data collections
Gene metrics:16Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| edema | 1 supporting dataset | Ncor2em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| long tibia | 1 supporting dataset | Ncor2Ncor2 | heterozygote | Early adult | 1.53x10-6 | ||
| increased startle reflex | 3 supporting datasets | Ncor2Ncor2 | homozygote | Early adult | 1.93x10-11 | ||
| abnormal blood vessel morphology | 1 supporting dataset | Ncor2em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Ncor2Ncor2 | homozygote | Early adult | N/A * | ||
| abnormal craniofacial morphology | 1 supporting dataset | Ncor2em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| abnormal placenta morphology | 1 supporting dataset | Ncor2em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| abnormal tail movements | 1 supporting dataset | Ncor2Ncor2 | heterozygote | Early adult | 1.7x10-5 | ||
| increased prepulse inhibition | 3 supporting datasets | Ncor2Ncor2 | heterozygote | Early adult | 1.32x10-6 | ||
| abnormal placenta morphology | 1 supporting dataset | Ncor2em1(IMPC)Mbp | homozygote | E15.5 | N/A * |
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External links
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| Ncor2em1(IMPC)Mbp | Exon Deletion | | mouse |
| Ncor2tm96110(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |