Nr1i2 | nuclear receptor subfamily 1, group I, member 2

GeneMGI:1337040Synonyms: PXR.1, PXR, +4 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased mean corpuscular volume1 supporting datasetNr1i2Nr1i2homozygoteEarly adult1.73x10-7 
increased circulating creatinine level1 supporting datasetNr1i2Nr1i2homozygoteEarly adult2.92x10-8 
increased circulating sodium level1 supporting datasetNr1i2Nr1i2homozygoteEarly adult7.91x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Nr1i2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Nr1i2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Nr1i2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter