Invs | inversin

Physiological systems

15 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging Cardiovascular system

12 No significant impact

9 Not tested

Gene metrics:3Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsInvsem1(IMPC)BayhomozygoteEarly adultN/A * 
hemorrhage1 supporting datasetInvsem1(IMPC)BayhomozygoteE18.5N/A * 
edema1 supporting datasetInvsem1(IMPC)BayhomozygoteE15.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Invsem1(IMPC)BayExon Deletionmouse
Invstm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Invstm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell
Invstm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Invstm33843(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Invstm40361(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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