Pigq | phosphatidylinositol glycan anchor biosynthesis, class Q

GeneMGI:1333114Synonyms: Gpi1, Gpih, +2 more

Physiological systems

20 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Embryo Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Hearing/vestibular/ear Craniofacial Mortality/aging Cardiovascular system

9 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:35Significant phenotypes

2Associated diseases

Expression examined in:50Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal tail bud morphology	1 supporting dataset	Pigq^{tm2b(EUCOMM)Wtsi}	homozygote	E9.5	N/A ^*
abnormal limb bud morphology	1 supporting dataset	Pigq^{tm2b(EUCOMM)Wtsi}	homozygote	E9.5	N/A ^*
pallor	1 supporting dataset	Pigq^{tm2b(EUCOMM)Wtsi}	homozygote	E9.5	N/A ^*
abnormal pericardium morphology	1 supporting dataset	Pigq^{tm2b(EUCOMM)Wtsi}	homozygote	E9.5	N/A ^*
abnormal hindbrain development	1 supporting dataset	Pigq^{tm2b(EUCOMM)Wtsi}	homozygote	E9.5	N/A ^*
abnormal midbrain development	1 supporting dataset	Pigq^{tm2b(EUCOMM)Wtsi}	homozygote	E9.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Pigq^{tm2b(EUCOMM)Wtsi}	homozygote	E9.5	N/A ^*
abnormal somite shape	1 supporting dataset	Pigq^{tm2b(EUCOMM)Wtsi}	homozygote	E9.5	N/A ^*
abnormal blood vessel morphology	1 supporting dataset	Pigq^{tm2b(EUCOMM)Wtsi}	homozygote	E9.5	N/A ^*
decreased total retina thickness	2 supporting datasets	Pigq^{tm2b(EUCOMM)Wtsi}	heterozygote	Early adult	2.1x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pigq.

Associated images

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Histopathology

There is no histopathology data found for Pigq.

IMPC related publications

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External links

No external links available for Pigq.

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*Pigq^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pigq^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Pigq^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pigq^{tm2b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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