Zfp148 | zinc finger protein 148

GeneMGI:1332234Synonyms: beta enolase repressor factor 1, ZBP-89, +3 more

Physiological systems

22 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Integument Embryo Growth/size/body region Behavior/neurological Skeleton Mortality/aging Renal/urinary system

15 No significant impact

2 Not tested

Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:50Adult tissues
62Embryo tissues

Phenotypes

abnormal embryo size1 supporting datasetZfp148tm1b(EUCOMM)HmguhomozygoteE18.5N/A * 
preweaning lethality, complete penetrance2 supporting datasetsZfp148tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
abnormal skin coloration1 supporting datasetZfp148tm1b(EUCOMM)HmguheterozygoteEarly adult4x10-5 
abnormal kidney morphology1 supporting datasetZfp148tm1b(EUCOMM)HmguheterozygoteEarly adultN/A * 
unresponsive to tactile stimuli1 supporting datasetZfp148tm1b(EUCOMM)HmguheterozygoteE18.5N/A * 
unresponsive to tactile stimuli1 supporting datasetZfp148tm1b(EUCOMM)HmguhomozygoteE18.5N/A * 
increased bone mineral density1 supporting datasetZfp148tm1b(EUCOMM)HmguheterozygoteEarly adult4.54x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zfp148tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Zfp148tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Zfp148tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Zfp148tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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