Ltbp4 | latent transforming growth factor beta binding protein 4

GeneMGI:1321395Synonyms: 2310046A13Rik

Physiological systems

15 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

10 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased grip strength1 supporting datasetLtbp4em1(IMPC)TcphomozygoteEarly adult8.36x10-5 
enlarged spleen1 supporting datasetLtbp4em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal sternum morphology1 supporting datasetLtbp4em1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ltbp4em1(IMPC)TcpInter-exon deletionmouse
Ltbp4tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Ltbp4tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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