Kcnj16 | potassium inwardly-rectifying channel, subfamily J, member 16

GeneMGI:1314842Synonyms: 6430410F18Rik, Kir5.1

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Skeleton

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased bone mineral content1 supporting datasetKcnj16tm1SjtuhomozygoteEarly adult4.44x10-9 
abnormal bone mineralization1 supporting datasetKcnj16tm1SjtuhomozygoteEarly adult2.7x10-7 
tremors1 supporting datasetKcnj16tm1SjtuhomozygoteEarly adult1.98x10-8 
abnormal startle reflex1 supporting datasetKcnj16tm1SjtuhomozygoteEarly adult2.49x10-5 
abnormal response to tactile stimuli1 supporting datasetKcnj16tm1SjtuhomozygoteEarly adult2.68x10-6 
abnormal bone structure1 supporting datasetKcnj16tm1SjtuhomozygoteEarly adult1.94x10-8 
decreased bone mineral density1 supporting datasetKcnj16tm1SjtuhomozygoteEarly adult2.74x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Kcnj16tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Kcnj16tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Kcnj16tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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