Cbr3 | carbonyl reductase 3

GeneMGI:1309992Synonyms: 1110001J05Rik

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Skeleton

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased exploration in new environment1 supporting datasetCbr3em1(IMPC)IcshomozygoteEarly adult8.88x10-5 
decreased thigmotaxis2 supporting datasetsCbr3em1(IMPC)IcshomozygoteEarly adult6.49x10-12 
decreased vertical activity1 supporting datasetCbr3em1(IMPC)IcshomozygoteEarly adult7.98x10-5 
decreased locomotor activity4 supporting datasetsCbr3em1(IMPC)IcshomozygoteEarly adult1.09x10-23 
decreased bone mineral density1 supporting datasetCbr3em1(IMPC)IcshomozygoteEarly adult9.07x10-6 
abnormal behavior1 supporting datasetCbr3em1(IMPC)IcshomozygoteEarly adult6.49x10-12 
decreased anxiety-related response1 supporting datasetCbr3em1(IMPC)IcshomozygoteEarly adult2.06x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cbr3em1(IMPC)IcsDeletionmouse
Cbr3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Cbr3tm96279(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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