Casq1 | calsequestrin 1

GeneMGI:1309468Synonyms: sCSQ, CSQ, +2 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased grip strength	4 supporting datasets	Casq1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.78x10^-9
abnormal freezing behavior	1 supporting dataset	Casq1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.6x10^-5
abnormal cholesterol homeostasis	1 supporting dataset	Casq1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.4x10^-6
increased circulating total protein level	1 supporting dataset	Casq1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.19x10^-6
decreased circulating creatinine level	1 supporting dataset	Casq1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.58x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Casq1.

Associated images

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Histopathology

There is no histopathology data found for Casq1.

IMPC related publications

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External links

No external links available for Casq1.

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*Casq1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Casq1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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