Lhx6 | LIM homeobox protein 6

GeneMGI:1306803

Physiological systems

22 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Behavior/neurological Mortality/aging

20 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

52Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	2 supporting datasets	Lhx6^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased locomotor activity	4 supporting datasets	Lhx6^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	3.14x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Lhx6^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lhx6.

Associated images

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Histopathology

There is no histopathology data found for Lhx6.

IMPC related publications

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External links

No external links available for Lhx6.

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*Lhx6^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Lhx6^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Lhx6^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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