Hcn4 | hyperpolarization-activated, cyclic nucleotide-gated K+ 4

GeneMGI:1298209

Physiological systems

20 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Mortality/aging

19 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

5Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes



preweaning lethality, complete penetrance	1 supporting dataset		Hcn4^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult		N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hcn4.

Associated images

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Histopathology

There is no histopathology data found for Hcn4.

IMPC related publications

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External links

No external links available for Hcn4.

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*Hcn4^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Hcn4^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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